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Why We Aging

  • Jul 8, 2009
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1. Free radical levels in our body has to be controlled in a small quantity to make them helpful to our body. Excessive free radicals created by the chemical process-- oxidation, are found to accelerate your aging. Because free radicals can acquire electron from other molecules in our body thereby left that molecule and/or cell damaged. Excess free radicals are more easily created through oxidation by environmental pollutions and radiations. Antioxidant is a group of molecules that can neutralize free radicals thereby is a common component in anti-aging skin care creams and anti-aging super foods/supplements.
2. Glycation here is a term referring to a type of chemical reaction between amino acids of the protein and aldehydes (such as glucose, sugar, called glycating agents). The glycating agents can cross link 2 proteins to form AGE (advanced glycation end products) by forming covalent bonds between protein and itself. AGE is very destructive to our body in that they can bind to cells causing them to produce toxic chemical by-products. Moreover, AGE can cause the production of free radicals which in turn produce more aldehydes glycating agent thereby forming a vicious cycle that will accelerate your aging. The natural substance discovered so far that is able to neutralize glycating agents is an expensive dipeptide nutrient called carnosine. The effect of glycation  is reflected as unsightly wrinkled skin. In addition, glycation can cause age-related degenerative diseases including the neurologic, vascular, and eye disorders. Glycation is commonly estimated by monitoring levels of glycosylated hemoglobin (Hba1c) in our blood.
3. Methylation refers to the chemical reaction whereby molecules containing methyl group can be linked to various constituents of protein, DNA and other molecules. Methylation in our body must be balanced in order to keep proteins, DNA and other molecules function well. Homocysteine is a byproduct of an important methylation process in our body after methionion (an amino acid) is used to methylate protein and DNA. Excess homocysteine has been implicated in aging in that homocysteine is believed to accelerate telemore (a structure involved in cell division) destruction. However, methylation of certain part of DNA can actually turn off unnecessary or detrimental genes and can block division of abnormal cells thereby reverse aging caused by these abnormal cells. How does our body balance methylation? There are three groups of molecules in our body regulate to balance methylation. They are vitamin B (B6 and B12), TMG (Tri-Methyl-Glycine, also known as Betaine), and SAMe (S-Adenosyl-Methionine). As we age, Vitamin B's function as a cofactor in methylation reaction tend to become less efficient. SAMe formed in the body by combining methionion and ATP (adenosine triphosphate) is the most effective methylating agent.
4. It is found that Chronic Inflammation is the cause of many age related damage, because excessive inflammation also produces excessive toxic chemicals which not only eliminate bacteria, but also destroy normal body cells. One example phenomenon of excessive inflammation is excitotoxicity where brain cells are over-excited. Another chemical factor in inflammation is tumor necrosis factor(TNF), excess TNF causes the degeneration of brain and nerves. Omega-s fish oil has been used for anti-inflammatory purposes, however it only deal with one component of inflammation. The best known natural calorie restriction mimics resveratrol (an anti-inflammatory and an antioxidant) has been used to keep TNF as low as possible
5. DNA degeneration is an aging process in which DNA lose its ability to interact with RNA, the molecule directs the translation and synthesis of protein (the macromolecule perform all the functions in our body). The degeneration is then passed on to the new cells after DNA replication and cell division and therefore accelerate aging. Because of this, bio-active DNA repair molecules are an essential part of anti-aging super foods.
6. It has been proposed that aging was partially a result of decreased energy production in the cell's mitochondria. In the presence of reduced mitochondrial function, cells become defective and lack the energy needed to effectively repair mutated or damaged DNA. This theory about the correlation of cell energy depletion and aging have been proved by many published scientific studies since its proposal.
It is important to understand that these main causes of aging are not isolated. Rather the 6 causes of aging are interrelated. Many free radicals can also increase glycation (AGE). To see more detailed picture of Aging Process, visit our web site

Author: dragon web profit
Anti-Aging Skin Care Web Site: http://www.antiagingskincarebeauty.com
Emai: dragonwebprofit@antiagingskincarebeauty.com

Post a comment Tags: aging, ageing, anti-aging, aging process, what are the causes of aging, molecular biology of aging, why we age, causes of aging …
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